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Their investigations revealed that insulin exerts a regulatory influence on cystathionine -synthase and BHMT, contributing to the intricate metabolic changes associated with diabetes mellitus

Role of GPX4 in health and disease Glutathione peroxidases (GPXs) are a family of selenoprotein antioxidant enzymes that utilize glutathione (GSH) to reduce hydrogen peroxide, and other hydroperoxides, preventing oxidative damage in the cell

Selective and synergistic activity of L-S,R-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase

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Levels decline with age

Other enzymes using glutathione as a substrate are glutaredoxins