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Second, they used ammonium acetate buffer at pH 10.2, whereas we used phosphate buffer at pH 7.5

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Maintaining optimal levels of glutathione appears to be important for supporting cognitive function, especially as we age.* The normal process of aging is associated with a decrease in glutathione regulation, which can result in increased oxidative activity.* Less than optimum levels of glutathione are observed in individuals experiencing a decline in cognitive function.* Conversely, individuals living over 100 years tend to have higher glutathione reductase activity.* A common mistaken belief is that glutathione is not well absorbed when its taken orally, but significant data confirms it is efficiently absorbed across the intestinal epithelium by a specific uptake system.* Glutathione-SR from Thorne Research represents an important breakthrough in glutathione supplementation

You can also explore the broader Immunity Essentials page if you want to see how antioxidant support fits into a wider wellness routine

40 GSH in Bacterial Physiology Biosynthesis, Metabolism, and Distribution GSH is synthesized through a two-step process involving peptide linkages (Figure 2)