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Phase 2 trial in primary mitochondrial cardiomyopathy

The interaction between oxidative stress and the inflammatory process may play a role in contributing to the development of airway remodeling induced by obesity

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Cellular adaptation to hypoxia involves an enhanced glycolytic flux, primarily mediated by HIF-dependent transcriptional upregulation of genes encoding glucose transporters and glycolytic enzymes

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However, this may be independent of cognitive changes (Johansson et al., 2022)