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Animals were randomly assigned to one of 4 groups of n 4-12 animals per group

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Graphical Abstract Access this article Similar content being viewed by others Abbreviations CBD: Cannabidiol THC: Tetrahydrocannabinol ECS: Endocannabinoid system FDA: Food and Drug Administration PD: Parkinsons disease AD: Alzheimer's disease HD: Huntingtons disease MAPK: Mitogen-activated protein kinase PKA: Protein kinase A CINV: Chemotherapy-induced nausea and vomiting IFN-: Interferon gamma TNF-: Tumor necrosis factor alpha CBRs: Cannabinoid receptor OR: Opioid receptors GPRs: G-protein coupled receptor FAAH: Fatty acid amide hydrolase 5-HT 1A : 5-Hydroxytryptamine receptor 1A GABA A : -Aminobutyric acid receptor PPAR-: Peroxisome proliferator-activated receptor TRPV: Transient receptor potential cation channel subfamily V References Earleywine M (2002) Understanding marijuana: a new look at the scientific evidence

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Bull attempted to reclaim his share of the market for his grape by offering direct bulk sales of the vines, as advertised at the bottom of this broadside, but he never saw the fruits of his laborhis tombstone epitaph read: He Sowed