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Terziroli Beretta-Piccoli B, Invernizzi P, Gershwin ME, Mainetti C

Nrf2 is a critical factor in the cellular response to antioxidant stress, which transcriptionally activates antioxidant proteins and cytoprotective genes by binding to antioxidant response element motifs to scavenge excessive intracellular ROS and mitigate oxidative damage 31

In genetically susceptible follicles, DHT binds to receptors and triggers miniaturization

In functional assays, DFO reduced P

Conclusions Detailed analysis of the results showed that the increased levels of AST, ALT and ferritin, although statistically significant, were within or slightly exceeded physiological norms