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They have crucial modulator roles in motor activities, motivation, drive, and cognition, and are widely dispersed throughout the brain

The viral hijack of human ACE2 receptor disrupts RAAS activation, upregulates NF-B pathway, triggers cytokine storm, hypertension, cell proliferation, inflammation, and fibrosis, where all elicit detrimental effects on every bodily organ during SARS-CoV-2 infection 635

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