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An analysis of serum samples from 30 ED patients showed significantly lower levels of hsamiR301a3p compared to healthy controls

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Together, these factors form an integrated molecular network in which NO-mediated perfusion facilitates nutrient delivery, leucine-driven mTOR activation supports muscle anabolism, and exercise-induced AMPK signaling maintains metabolic efficiencycollectively counteracting the anabolic resistance associated with aging

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Other studies have confirmed that NRF2, speedy/RINGO cell cycle regulator family member A (SPY1), and myeloperoxidase (MPO) regulate ferroptosis and lipid peroxidation in motor neurons, thereby modulating neural function