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During glutamine deprivation, Teff cells show decreased c-MYC protein expression, growth restriction, and impaired immune function [85].In addition, glutamine deprivation promotes the differentiation of Treg cells through AMPK-mTORC1 signaling pathway, thereby reducing the immune function of Teff cells [86, 87].In summary, the reprogramming of glutamine metabolism in T cells regulates the differentiation and function of T cells from various aspects, thereby regulating the immune response of the body (Fig

The cells were then washed with PBS and analyzed on FACS

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Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis

E., & Rosenberg, I

Glutathione peroxidase 1 (Gpx1) is first identified as a selenium-dependent enzyme in 1973 and has a role as antioxidant enzyme