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The British Dietetic Association recommends 10 mcg daily or 2,000 mcg weekly supplements, as absorption efficiency decreases with higher single doses

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However, this simultaneously allows time for hypoxic cells to reoxygenate and any remaining tumor cells to proliferate, reducing the clinical outcome of both treatments (Saggar and Tannock, 2015)

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These findings emphasize the fact that the cellular anti-oxidative defense system contains many compensatory mechanisms to allow survival

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