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Notably, one promising avenue involves leveraging the astrocytic urea cycle to enhance neuroprotection and facilitate a liver-like clearance mechanism in the brain, offering potential strategies for mitigating neurodegenerative processes 59,73

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Moreover, a distinct OL population (peri-neuronal OL) has been identified in gray matter regions 81

the subject in need thereof may be a subject identified as being a responder based on: the subjects and control groups may be children

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