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This article systematically reviews the research hotspots in organ cross-talk in health and disease, elucidating the signaling pathways and mechanisms involving the brain, heart, and gut, thereby providing a theoretical and practical foundation for advancing studies on disease progression and novel therapeutic strategies

Laboratory protocols demonstrate that the peptide neutralizes doxorubicin-induced chemotoxicity and shows that research targeting of senescent cells is feasible even after health decline has occurred

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However, contrary findings indicate that FRDA-derived B cells exhibit increased resistance to erastin-induced ferroptosis compared to controls (387)

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