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Figure 4 Macrocyclic Angiotensin IV Analogues The capability of IRAP to degrade physiologically important cyclic peptides has inspired the development of macrocyclic analogues of Ang IV

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These agents include diethylenetriaminepentaacetic acid (DTPA)(7, 8), chelation therapy for transuranic radionuclides, potassium iodide (9) for radioisotopes of iodine, and hexacyanoferrate (II) called Prussian Blue(10) for radioisotopes of cesium and thallium

Activity of caspase-8 determines plasticity between cell death pathways

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