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doi: 10.14719/pst.1621 194 SrivastavaS.SrivastavaA

Apoptotic cell bodies: Lymphocytes from SLE patients frequently experience accelerated apoptosis, releasing nuclear antigens like nucleosomes into the extracellular space, which can then trigger immune responses and autoantibody formation (84)

Among previously suggested pathways are lipotoxicity arising from ectopic accumulation of fat in tissues other than adipose, such as liver and muscle (Mantzaris et al., 2011