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K., Henkel, J

Pt 1, pp

The efficacy of this therapeutic combination was first validated in our breast cancer models, demonstrating that PHGDH wild type breast cancer cells do not respond to the therapeutic combination, whereas PHGDH-amplified breast cancer cells exhibited a synergistic sensitivity to suboptimal dosages of sertraline plus chloroquine (Figure S8A)

While there is no treatment or way to prevent the metallic taste due to chemotherapy drugs, certain measures can help, such as avoiding metal utensils, which can increase the sensation of a metallic taste, and serving food cold or at room temperature to slightly mask the taste of food

That separation is the main reason this combination is pharmacologically rational

ATF6 deficiency in microglia attenuates inflammation in autoimmune encephalomyelitis by promoting NF-B p65 degradation (202)