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Nat Rev Urol 2019;16:172-86

Acta 1854, 624631

We found that mitochondrial dysfunction induced by palmitoyl-L-carnitine leads to calcium overload and activation of kinases that contribute to tau hyperphosphorylation

The results indicated that the upregulation of miR-195 inhibited the production of proinflammatory cytokines, including iNOS, IL-6, and TNF-, while enhancing the release of anti-inflammatory cytokines such as IL-4 and IL-10 in LPS-treated BV-2 cells