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This phenomenon, known as metabolic endotoxemia, has been linked to: Chronic inflammation Insulin resistance Obesity Metabolic syndrome In animal studies, even modest increases in circulating endotoxins have been shown to trigger inflammatory responses that interfere with metabolic regulation

doi:10.1016/j.bcp.2018.05.003 Neelakantan H, Brightwell CR, Graber TG, et al