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IV doses of 25-400 mcg/kg for safety studies Important: These are experimental doses used in animal studies and cannot be extrapolated to other species due to significant differences in metabolism, pharmacokinetics, receptor expression, peptide degradation rates, and tissue distribution patterns

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[10] Other uncommon adverse effects reported with very high doses include dermatological lesions (photosensitivity and skin rash), gastrointestinal upset, and in some cases dependency syndromes (e.g

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