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However, natural glutathione levels decline with age, environmental toxins, stress, alcohol, and poor diet

Given that GMSCs are of a neural crest origin [18, 35, 36], our previous studies have shown that ex vivo expanded GMSCs could directly convert to NCSC-like or neural progenitor-like cells under defined culture conditions, which exerted better therapeutic effects on axonal regeneration and functional recovery of injured peripheral nerves than their parental GMSC counterparts [34, 41]

10.1126/scisignal.2004235 15

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