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Description

Malfunctioning of the iron-sulfur cluster assembly machinery in Saccharomyces cerevisiae produces oxidative stress via an iron-dependent mechanism, causing dysfunction in respiratory complexes

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mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT

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This dual action, increasing fat breakdown while blocking fat formation, creates a metabolic environment that favors net fat loss even when caloric intake is not dramatically reduced