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Holick, New England Journal of Medicine , 2007)

Reduction of dietary fat absorption by the novel gastrointestinal lipase inhibitor cetilistat in healthy volunteers

Furthermore, it overlaps the bipartite nuclear localization signal (NLS) and contains both the RRL motif, involved in electrostatic interaction with MVI partners, and the positively charged region (WKSKNKKRN), involved in PIP 2 binding (Tumbarello et al., 2013