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Transferrin receptor 1-targeted polymersomes therapy for colorectal cancer

In healthy cells, p53 activation can initiate DNA repair or apoptosis depending on damage severity

This stress can initiate some catastrophic events in the cells such as lipid peroxidation, formation of DNA adducts, protein crosslinks, and the reduction of endogenous antioxidant levels in the liver 6

70 As cells use NADPH to reduce cystine to cysteine, the increased cysteine catabolism by CDO implies the increased consumption of NADPH, which will affect other cell metabolic pathways and the antioxidant capacity as well

The cytoprotective role of the Keap1-Nrf2 pathway

T le explicas el transporte de cidos biliares, la inhibicin de la adipognesis