glutathione s transferase location Frontiers General reaction catalyzed by glutathione

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I infected 9 CC lines with LACV and identified diverse susceptibility phenotypes among the lines

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This phenotype suggests that an antiviral mechanism was blocking phage infection, such that expressing a phage gene that inhibits the relevant defense in the host could alleviate restriction

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Importantly, some fungal-specific enzymes offer high target selectivity with minimal risk to the host