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Neurological symptoms may also be observed such as: subacute mild encephalopathy, affecting memory & concentration, chronic mild axonal polyneuropathy, manifested as distal paresthesias, radicular pain (less common), some rare ones include encephalomyelitis & leukoencephalopathy

Overall, our results demonstrate that p53 signalling in adipocytes dictates LAM accumulation in AT under IF and modulates fasting effectiveness in mice and humans