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Further development of TGR-based therapeutic approaches is impeded by the lack of non-covalent small molecule inhibitors of TGR, a well-known and general problem for all the members of the high molecular weight, Sec-containing TrxR subfamily that are considered attractive and unexploited drug targets for several human diseases 21,22

For more education on this topic, How to Keep Your Cells Healthy as You Age expands on the broader healthy ageing picture

doi: 10.1016/j.tem.2015.01.006 207 IizukaKTakaoKYabeD

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The role of FOXO1 in beta-cell failure and type 2 diabetes mellitus

CrossRef Management of Bleeding from Unresectable Gastric Cancer Hideaki Kawabata, Misuzu Hitomi, Shigehiro Motoi Biomedicines.2019