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Biotin depletion exacerbated neurotoxicity in flies lacking the enzyme biotinidase, whereas biotin supplementation reversed Mn-induced pathology in wild-type flies, revealing the therapeutic potential of using biotin to treat Parkinsonism phenotypes

Best Pract Res Clin Gastroenterol 27(4):577596 Valente MJ et al (2012) Contribution of oxidative metabolism to cocaine-induced liver and kidney damage