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Patients with significant medical history (kidney disease, severe asthma, certain medications) should disclose them in the pre-procedure assessment

Journal of Neuroscience, 43 , 82318242

This review aims to provide a guide to the management of this complex condition

A role of oxidative stress in GO is supported by a number of basic studies suggesting that ROS promote the proliferation of OFs and the release of GAGs, the synthesis and secretion of cytokines, and the expression of other factors involved in the pathogenesis of GO, namely heat shock protein 72 (HSP-72), HLA-DR and ICAM-1 ( Figure 1 In this context, a number of studies, performed both in vitro and in vivo , investigated the effects of antioxidant agents in GO, including selenium, pentoxifylline, quercetin, enalapril, vitamin C, N-acetyl-L-cysteine and melatonin ( Oxidative Stress and Proliferation of Orbital Fibroblasts Burch et al

Notopterol mitigates osteoarthritis progression and relieves pain in mice by inhibiting PI3K/Akt/GPX4-mediated ferroptosis

Each possesses an amphipathic helix (APH) with high affinity for phosphatidylserine (PS), a specific phospholipid found in the inner leaflet of the PM 12,13