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Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

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Important considerations include the underlying condition being treated, the duration of therapy and patient-specific factors, such as the risk of relapse and reported side effects

As such, these findings provide new insights into the link of psychiatric disorders with snuff use and chewing tobacco

Citations: Beutel, M