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Shandong: Shandong University of Traditional Chinese Medicine

Abstract Tumor heterogeneity is a fundamental driver of therapeutic resistance across solid malignancies, arising from genetic, epigenetic, phenotypic, spatial, temporal, and microenvironmental diversity

Individuals with Laron syndrome who carry mutations in the growth hormone receptor ( GHR ) gene that lead to severe congenital IGF-1 deficiency with decreased insulin/IGF-1 signaling (IIS) exhibit reduced prevalence rates of acne, diabetes and cancer

Using preclinical animal models, they examined the involvement of the nervous system in inflammation through the psychoneuroimmunoendocrine axes

Still, the elicited antibodies did not neutralize Bb in vitro (Fig