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Description

Within this scenario, distinct subsets of macrophages, endowed with high rates of heme catabolism by the stress-responsive enzyme heme oxygenase-1 (HO-1), play critical roles in physiologic and pathological conditions

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In addition, the high penetration level through the stratum corneum alone can be explained by the fact that there was no tissue retention from underlying skin that may have limited penetration

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Yaohua Zhang, Capital Medical University, China

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