foxo4-dri peptide senolytic mouse study 2023 induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOX04 DRI FOXO4 peptide targets myofibroblast ameliorates bleomycininduced pulmonary fibrosis in mice through ECMreceptor interaction pathway Han 2022 Journal of Cellular and Molecular Medicine Wiley Online Library FOXO4 DRI Results: What to Expect (2026) Peptide inhibitors targeting FOXO4 p53 interactions and inducing senescent cancer cell specific apoptosis bioRxiv FOXO4 DRI Wikipedia
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