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3 Neurochem Int [Gly14]-Humanin protects against beta-amyloid via mitochondria (Jin et al., 2009)HNG preserved mitochondrial membrane potential, blocked cytochrome-c release and reduced apoptosis in amyloid-beta-exposed PC12 cells

In 2023, Qi et al., 2023 reported that the antidiabetic drug mitoglitazone (MGZ) upregulated GPX4 and reduced lipid peroxidation, thereby significantly alleviating renal injury in mice after I/R, providing a new therapeutic strategy to ameliorate renal I/R injury

Zn reduced the ROS production through enhanced anti-oxidant activities (APX, CAT, POD, and SOD)

In this review, the development of tamoxifen resistance in breast cancer is discussed, with special emphasis on the effects of some newly discovered enzymes and transcription factors on tamoxifen resistance, the protective autophagy of cells, and the latest progress in cell cycle regulators

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Diabetic neuropathy plagues thousands of older adults