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The laboratory has demonstrated that Rac GTPases are key regulators of the engraftment and mobilization functions of hematopoietic stem cells

2017;12:e0175582

Oral treatment is recommended because of the ease of intestine absorption compared to cutaneous absorption and the decreased risk of phenol moiety autooxidation

Thus, our data further indicate that the increased mTORC1 signaling is a consequence of GSH depletion, but it is not sufficient to sustain humoral immunity