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References Doniach D, Roitt IM, Taylor KB

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Following treatment with 0.5 mg/mL LPC, an initial increase in GFAP+ expression is observed over a 72-h period when compared to that of untreated slices, but with further time in culture, no difference in GFAP+ expression is seen between untreated and LPC-treated slices

Greenway FL, Fujioka K, Plodkowski RA, Mudaliar S, Guttadauria M, Erickson J, et al

All treatments are administered by trained healthcare professionals using high-quality formulations in a clean, clinical setting

That slowdown signals metabolic adaptation, and that is when a second agent with a different mechanism provides the most benefit