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doi:10.1371/journal.pone.0000625

Why Stimulant-Free Matters

In addition to a kinetic response to changes in Cys concentration, the catalytic turnover of Cys by CDO leads to conversion of CDO to its mature (Cys-Tyr cofactor-containing) form that has a markedly increased catalytic efficiency (k cat /K m ) and longer catalytic half-life, as discussed earlier

Liu MR, Zhu WT, Pei DS

Alfayez M, Kantarjian H, Ravandi F, Konopleva M, Jabbour E, Garcia-Manero G, Kadia T, Borthakur G, DiNardo C, Estrov Z, Pemmaraju N, Pierce S, Yilmaz M, Short N, Takahashi K, Assi R, Andreeff M , Cortes JE, Daver N

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