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FIGURE 1 2.2.1 DNA vaccine As nucleic acid vaccines are flexible in antigen selection and are relatively fast, cheap and efficient to produce, DNA vaccines are widely recognized to induce precise and effective immune responses ( ESR1 mut + BC and the development of ESR1 mut-mediated endocrine therapy resistance ( The rapid development of nanotechnology and bioinformatics has greatly contributed to improvement and optimization of DNA vaccines, which not only provides more epitope information, but also enables simultaneous delivery of multiple components and induces a stronger immune response

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