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In the Phase 2 trial, the cohorts that escalated to higher maintenance doses began at 2mg weekly and increased by 2mg every 4 weeks

Stacking & Combinations Because its mechanism is NAD+ preservation, the logical research pairing is with the NAD+ pathway : in some research framings, an NNMT inhibitor like 5-Amino-1MQ is discussed alongside NAD+ precursors, on the reasoning that inhibiting the enzyme that drains NAD+ and supplying more NAD+ substrate address the same bottleneck from two directions

So the research that were reading, that we think is so important, is leading us through certain areas

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The glutathione-S-transferase (GST) enzyme family conjugates GSH onto electrophilic xenobiotics drug metabolites, environmental toxins, carcinogens, and reactive intermediates

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