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Options for patients with UC include: Removes the colon and rectum

Months six to twelve: optimization Continued improvement typically occurs through month twelve and beyond

Twenty-nine participants with erosive OLP accompanied by stage IIIV periodontitis will be recruited from the Department of Oral Mucosal Diseases at the Ninth Peoples Hospital affiliated to Shanghai Jiao Tong University School of Medicine (main center), Department of Stomatology at Shanghai Baoshan Hospital (sub-center I), Periodontal Disease Department of the First Affiliated Hospital of Xinjiang Medical University (sub-center II), Stomatology Hospital affiliated to Zhejiang University School of Medicine (sub-center III), and Department of Stomatology at Huashan Hospital (sub-center IV)

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Together, these observations point to a transitory senescent-like cell population that is abundant at the self-renewing MuSC 1 stage across all ages, but increases in older mice, potentially underlying a stalled stem cell self-renewal in mouse muscle aging