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These include: Hemodialysis Hemodialysis also often involves blood transfusion and/or administration of erythropoietin or its analogs either of which also require a TUE Treatment for Sickle Cell Disease involves homologous blood transfusions which are prohibited If an athlete requires a Prohibited treatment involving the removal and reintroduction of blood into the circulation for any legitimate medical condition, they should apply for a Therapeutic Use Exemption (TUE) before undergoing the treatment

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5,6 It also inhibits tyrosinase activity and melanosome transfer from melanocytes to keratinocytes

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Their work includes chronic dosing studies extending to 6 weeks, comprehensive tissue examination at necropsy, and genetic toxicology assessment using standardized protocols accepted by regulatory agencies worldwide

Clinical concerns What actions will you initiate when you see someone whose diagnoses include impaired gastric acidity and/or Intrinsic Factor, and prescribed B12 injections, will you - - check B12 levels and clarify status