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b , TNF production by classical monocytes from a local control (Ctrl), P1 and P2 and the healthy brother of P1 without (NS) and with stimulation with LPS, BCG or L

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Increasing NAD + levels by supplementing NR in mouse tissues and mammalian cells activates SIRT1 and SIRT3, which ultimately leads to increased oxidative metabolism and prevents metabolic abnormalities induced by HFD

doi: 10.1038/s41580-019-0190-7 130 BrownMSRadhakrishnanAGoldsteinJL