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Higher bioavailability: Injection may offer more complete absorption than nasal delivery

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A further small study done recently on 10 paediatric patients similarly found that intranasal OH-Cbl normalised serum B12 levels in deficient patients ( Subcutaneous B12 Subcutaneous B12 is occasionally used, especially in patients with inborn errors of cobalamin metabolism, who need high pharmacological doses of B12 to maintain their B12-dependent metabolic pathways and related biochemistry within normal range

Patients may achieve additional weight loss, typically around 5-10% of their body weight, though results vary considerably between individuals