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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Wu S.-S., Li Q.-C., Yin C.-Q., Xue W., Song C.-Q

Although inflammation can be a protective response, sustained activation of neuroinflammatory pathways leads to neuronal injury and causes the progression of neurodegenerative disorders ( 2.5 Impaired protein degradation systems Dysfunction in systems responsible for protein degradation, such as the ubiquitin-proteasome system (UPS) and autophagy, contributes to the development of AD and PD

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Inflammatory responses and inflammation-associated diseases in organs

However, some parents of children with CAH, as well as several patients with CAH, do not agree with this rigorous recommendation