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For patients whose primary complaint is metabolic with poor sleep as a contributor CJC-1295/Ipamorelin or sermorelin may be more appropriate entry points, as the GH secretagogue literature is more robust

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Per the FDA-approved label, tirzepatide is titrated starting at 2.5 mg weekly and moving through 5, 7.5, 10, 12.5, and 15 mg at minimum intervals