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First, the present study was designed in a cross-sectional manner

Emerging lines of evidence indicate that E3 exerts a critical regulatory function in oxidative stress homeostasis, primarily through the transcriptional upregulation of pivotal antioxidant enzymes, including superoxide dismutase (SOD) and glutathione peroxidase (GPx)

Activation of those genes, in turn, has been shown to extend the lifespan in a wide variety of organisms and to reduce the incidence of age-related diseases, such as diabetes, cancer, immune deficiencies, and cardiovascular disorders (Bordone and Guarente 2005)

The most closely related bacterial sequence in Uniprot [104] is from the cyanobacterium Nostoc spec

FOS is found in onions, leeks, chicory, Jerusalem artichokes, and burdock root

Targeting these mitochondrial dependencies has emerged as a promising therapeutic strategy in CRc [6]