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An in vitro study (67), where human ectopic endometriotic cells were cultured with curcumin, showed a significant inhibition of TNF--induced secretion of IL-6, IL-8 and MCP-1 , known actors in the development of endometriosis

Several autophagic genes (e.g., ATG4, ATG5) are expressed in the mouse cochlea from the embryonic phage until the adult phage ( ATG4 -null mice show the common pathological features of the inner ear (Mario et al., 2010)

Obesogenic adipogenesis highly occurs in visceral white adipose tissue (vWAT), inducing prolonged adipose tissue expansion, inflammation, and systemic insulin resistance [5, 21]

The exact mechanism of ferroptosis induction and its interaction with cancer cells is also not fully understood, and further studies are needed to elucidate how this pathway can be efficiently manipulated ( To translate these findings into clinical practice, further investigation is needed to elucidate the molecular mechanisms of ferroptosis, explore potential combinatory therapies, and develop robust biomarkers

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For many experiment, we also used 10 nM of ligand for stimulation, which is a more physiological level than the 100 nM used in many previous experiments