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Ethics statement The animal study was reviewed and approved by the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA), New Delhi, India, and the Departmental Animal Ethical Committee (DAEC) of the University of Rajasthan, Centre for Advanced studies (CAS), Jaipur, India, has approved this study vide approval number 1678/90/re/S/12/CPCSEA dated 16 June, 2017

In addition to being used to synthesize glutamate, glutamine is incorporated into many proteins and can be used for nucleotide synthesis

Hajime H, Tomohiro W, Ken K, Kosuke M, Masatoshi K

In contrast, TP53, regulates apoptosis and oxidative stress responses but is often dysregulated in neurodegeneration

The remaining 2 of 12 patients rated their success at 80%, with most symptoms resolved but about 20% of their symptoms lingering

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