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The MASH trials primary endpoint was histologic improvement a validated surrogate, but still a surrogate

Mediators Inflamm 2013

Krauss, U

Bolton PF, Roobol M, Allsopp L, Pickles A

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Although it still exists in rural areas where treatment is not readily available, Se administration offers a preventative measure and is reputed to protect the infected myocardium against oxidative stress [82]