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Interestingly, although lipid peroxidation amplifies PARP-1 activation, inhibiting PARP-1 can significantly reduce lipid peroxidation and maintain mitochondrial integrity, underscoring the link between PARP-1 overactivation and oxidative damage in promoting parthanatos [142, 143]

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Lipin-1 is a phosphatidic acid phosphatase that controls the synthesis of phospholipid for membrane biogenesis

10.1016/j.foodchem.2024.138916 Food Chem

Narla, A

& Sethares, C

Combination of molecular adsorbent recirculating system and raioiodine for the treatment of concurrent hyperthyroidism and severe liver dysfunction: A retrospective cohort study