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In in vitro assays, there are various plants that show a cytotoxic effect on AML cells through different mechanisms ( In addition to the role of natural products in PCD, they may also prevent resistance by tumor cells to conventional chemotherapeutics (Yuan et al., 2017), thanks to their intervention in tumor metabolism (Figure 3)

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Regarding molecular mechanism of ROS against biomolecules, free species like NO , NO 2 , H 2 O 2 , and ONOO - can cross lipid membranes and carry signals across organelles, while other types of ROS have limited half-life or physical properties that contribute to damaging of other biological molecules

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doi: 10.1016/j.cell.2016.10.027, [DOI] [PMC free article] [PubMed] [Google Scholar] Shi F., Zhang G., Li J., Shu L., Yu C., Ren D., et al

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For each obtained lipidome (ER, mitochondria, whole cell), mol percent were calculated and used for final evaluation

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If a rash is still spreading or worsening past 48 hours, contact your prescriber that timeline distinguishes a normal local reaction from one that needs evaluation

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