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Results of the study concluded that wheatgrass extract acts similarly to PD98059, which selectively inhibits the extracellular signal-regulated kinases 1 and 2 (ERK 1/2) pathway, decreasing the expression of the mucin gene in response to hypoxia

Furthermore, bavachin upregulated the expression of the transferrin receptor and DMT1 while downregulating the expression of FTL and FTH

AI predicts drug-target-disease associations by analyzing large-scale biological networks (such as PPI networks), aiding drug repurposing and significantly reducing research and development costs (Tran et al., 2023

The female mice (homozygous for Hba tm1(HBA)Tow and heterozygous for Hbb tm2(HBG1,HBB*)Tow and Hbb tm3(HBG1,HBB)Tow [h/h:: A / S ], sickle-cell trait mice) and male mice (homozygous for both Hba tm1(HBA)Tow and Hbb tm2(HBG1,HBB*)Tow [h/h:: S / S ], sickle SCD mice) were bred to generate SCD mice