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206 YinJ.SakamotoK.ZhangH.ItoZ.ImagamaS.KishidaS.et al (2009)

The treatment, which was previously indicated only for symptomatic children 3 years of age and older with late infantile CLN2 disease, also known as Batten disease, can now be given to diagnosed children of all ages, regardless of whether they are symptomatic or presymptomatic

Whether it produces meaningfully better outcomes than once-daily dosing in humans remains unknown

Think safer, proven steps first, like lifestyle adjustments, medical screenings, and science-backed therapies

Activity at picomolar concentrations

Pineyro G, Archer-Lahlou E: Ligand-specific receptor states: Implications for opiate receptor signalling and regulation